Study: Automated Endoscopic Suturing Aids Significant Weight Loss

A new study by Israeli medtech startup Nitinotes shows that its fully automated endoscopic suturing system EndoZip is effective in achieving significant weight loss. 

Endoscopic suturing – placing medical stitches inside the gastrointestinal tract without invasive surgery – is used to reduce the size and capacity of the stomach (gastroplasty), thereby making a person feel satiated after less food and reducing their calorie intake.

Nitinotes says its automated, minimally invasive system simplifies and speeds up endoscopic gastroplasty procedures, offering a widely available and effective solution for hundreds of millions of patients living with obesity but for whom traditional bariatric surgery is not an option.

The study found that EndoZip can help a person reduce their body weight by 13 percent over a 12-month period, as well as boost other metabolic health indicators crucial to managing obesity-related comorbidities. 

According to the company, the findings show that EndoZip is a viable alternative to existing minimally invasive obesity treatments, expanding the options of patients who might not qualify or do not want to undergo traditional surgeries. 

The results of the study were published in the prestigious GIE: Gastrointestinal Endoscopy journal.

“The acceptance of our study for publication in GIE validates the potential of EndoZip technology [and] aligns with our mission to enhance the accessibility and reduce the invasiveness of obesity treatments,” said Nitinotes CEO Lloyd Diamond. 

“We believe EndoZip could help more physicians incorporate this technology into their practices, providing an additional option for patients seeking alternatives to traditional medical and surgical interventions,” he said.