This article was first published by The Times of Israel and is re-posted with permission.
New Israeli research may pave the way for drugs that “turn off the hunger switch” in the human brain with minimal side effects, scientists say.
A receptor in the brain, melanocortin 4 (MC4), is known to control the urge to eat. It has been dubbed the “hunger switch.”
A genetically inherited malfunction with this receptor is believed to be the most common cause of obesity that is triggered by a single gene mutation, impacting an estimated 5 percent of early-onset childhood obesity.
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